Rav Yisrael Yitzchok was the son of Rav Yissochor Dov, the Sabba Kadisha of Radoshitz, and the son-in-law of Rav Yehuda Leib Horowitz, who was the son of Rav Reuven of Dzernovtza, mechaber of Dudo’im Basodeh.
He received the Chassidic tradition as a talmid of his father and from Rav Yisrael of Rizhin, Rav Yechezkel of Kozhmir, Rav Chaim Meir Yechiel of Mogolintza and Rav Eliezer of Dzhikov.
In the year 5603, the Chassidim forced the position of Rebbe on him, but he continued to conduct himself with modesty and humility as before.
Like his father, the Sabba Kadisha of Radoshitz, he was renowned for his many wonders and miracles. He always received everyone with a smiling face.
He had good relationships with the other Tzaddikim of his generation, including: Rav Chaim of Sanz, Rav Yitzchok Meir of Ger (the Chiddushei HaRim), Rav Yosef Boruch of Neustadt, Rav Yitzchok of Vorka and Rav Yeshayohu of Praga.
At the young age of forty-eight he was struck by a very serious illness that racked his body with such pain and suffering that the famed Dr. Bernhard is said to have remarked that no human being should be able to endure such pain and suffering! He left for Warsaw to seek medical care and treatment and there he was niftar on 2 Kislev 5618. He was laid to rest in Warsaw.
Rav Nosson Dovid of Shidlovtza was extremely bitter and upset over his passing and said that had he had with him two more Tzaddikim, he would have ascended on high to demand an explanation as to why he was niftar at such a young age.
His sons were Rav Yaakov Dovid of Radoshitz and Rav Eliezer Yeruchem (son-in-law of Rav Chaim of Sanz). The rest did not take up rabbinical positions either as Rebbes or as Rabbonim. His sons-in-law were: the son of Rav Tudrus Lerrer of Chelm, Rav Avrohom Yehoshua Heschel Shapira of Mogolintza and Rav Tovia Lipschitz of Brigel.
