The Ralbag says that the situation with Yaakov was just about lost, and Yaakov wasn’t Mya'esh. The Me’am Lo’ez says that from here we learn that if you visit a sick person who appears to be more dead than alive, Rachana Litzlan, you must still daven, and it’s a sin not to! וֹמְצַﬠ שֵׁאיַיְתִי לַא ,םָדָא לֶשׁ וֹראָוַצ לַﬠ תַחַנוּמ הָדַח בֶרֶח וּליִפַא םיִמֲחַרָה ןִמ ברכות י א even if a sharp sword is resting on a person’s neck, he shouldn’t lose hope! Even though everyone is saying that for sure this sick person’s life is over!
In Novardok, when they learned Mussar on Bitachon, they would demand from themselves Bitachon; i.e., how can you NOT have Bitachon; after all the wonders that you’ve seen? יִב וּניִמֲאַי אֹל הָנָא דַﬠְו הֶזַּה םָﬠָה יִנֻצֲאַנְי הָנָא דַﬠ וֹבְּרִקְבּ יִתיִשָׂﬠ רֶשֲׁא תוֹתֹאָה לֹכְבּ שלח יד יא After all the miracles I did for them, when will they finally believe in Me?? The Bais HaLevi says that being afraid and not having Bitachon is a sin, and: שֵׁקוֹמ ןֵתִּי םָדָא תַדְּרֶח משלי כט כה this sin (of worrying) invites problems, which come as a punishment for not having Bitachon. Yet, we see how people are always worried, and working on Bitachon isn’t easy.